(1R,4S)-4-amino-1,2,3,4-tetrahydronaphthalen-l-ol is a chiral amino alcohol with the molecular formula C10H13NO, featuring a tetrahydronaphthalene ring system. (1R,4S)-4-amino-1,2,3,4-tetrahydronaphthalen-l-ol possesses a chiral center at the carbon 1 position, leading to the existence of two enantiomers, (1R,4S) and (1S,4R). Its unique structure and functional groups make it a valuable building block in the synthesis of pharmaceuticals and other biologically active compounds, as well as having potential applications in organic synthesis and medicinal chemistry.
1351997-20-0
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Basic information
- Product Name: (1R,4S)-4-amino-1,2,3,4-tetrahydronaphthalen-l-ol
- Synonyms:
- CAS NO:1351997-20-0
- Molecular Formula:
- Molecular Weight: 163.219
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (1R,4S)-4-amino-1,2,3,4-tetrahydronaphthalen-l-ol(CAS DataBase Reference)
- NIST Chemistry Reference: (1R,4S)-4-amino-1,2,3,4-tetrahydronaphthalen-l-ol(1351997-20-0)
- EPA Substance Registry System: (1R,4S)-4-amino-1,2,3,4-tetrahydronaphthalen-l-ol(1351997-20-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1351997-20-0(Hazardous Substances Data)
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1351997-20-0 Usage
Uses
Used in Pharmaceutical Synthesis:(1R,4S)-4-amino-1,2,3,4-tetrahydronaphthalen-l-ol is used as a building block for the synthesis of pharmaceuticals and biologically active compounds due to its unique structure and functional groups. Its chiral nature allows for the development of enantiomer-specific drugs, which can exhibit different pharmacological properties and reduce potential side effects.
Used in Organic Synthesis:
(1R,4S)-4-amino-1,2,3,4-tetrahydronaphthalen-l-ol is used as a key intermediate in organic synthesis, enabling the creation of a variety of complex organic molecules. Its versatile functional groups, including the amino and hydroxyl groups, facilitate various chemical reactions, such as condensation, substitution, and rearrangement, making it a valuable component in the synthesis of natural products, agrochemicals, and other specialty chemicals.
Used in Medicinal Chemistry:
(1R,4S)-4-amino-1,2,3,4-tetrahydronaphthalen-l-ol is used as a starting material or a scaffold in medicinal chemistry for the design and development of novel therapeutic agents. Its tetrahydronaphthalene ring system can be further modified and functionalized to create new chemical entities with potential biological activities, such as antimicrobial, antiviral, or anticancer properties. Additionally, its chiral center allows for the exploration of enantiomer-specific drug candidates, which can lead to improved efficacy and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 1351997-20-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,1,9,9 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.Calculate Digit Verification of CAS Registry Number 1351997-20:
(9*1)+(8*3)+(7*5)+(6*1)+(5*9)+(4*9)+(3*7)+(2*2)+(1*0)=180
180 % 10 = 0
So 1351997-20-0 is a valid CAS Registry Number.
1351997-20-0Upstream product
1351997-20-0Downstream Products
- 1443247-15-1 1-{5-tert-butyl-2-[3-(2-hydroxyethylsulfanyl)-phenyl]-2H-pyrazol-3-yl}-3-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea
- 1443247-13-9 1-(5-tert-butyl-2-(4-methoxy-phenyl)-2H-pyrazol-3-yl)-3-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea
- 1443247-53-7 C31H31Cl2N7O2
- 1443247-37-7 1-[5-tert-Butyl-2-(3-morpholin-4-yl-phenyl)-2H-pyrazol-3-yl]-3-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea
- 1443248-40-5 1-[5-tert-butyl-2-(3-hydroxy-phenyl)-2H-pyrazol-3-yl]-3-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea
- 1443248-38-1 1-[5-tert-butyl-2-(3-triisopropylsilanyloxy-phenyl)-2H-pyrazol-3-yl]-3-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea
- 1443247-33-3 1-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-3-(2-p-tolyl-2H-pyrazol-3-yl)-urea
- 1443248-25-6 4-(3-tert-butyl-5-{3-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-ureido}-pyrazol-1-yl)-piperidine-1-carboxylic acid benzyl ester
- 1443251-52-2 1-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[(1S,4R)-4-(3-isopropyl[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydronaphthalen-1-yl]urea
- 1443251-70-4 1-{5-tert-butyl-2-[3-(2-dimethylaminoethoxy)phenyl]-2H-pyrazol-3-yl}-3-[(1S,4R)-4-(3-isopropyl[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydronaphthalen-1-yl]urea
- 1443251-66-8 N-(4-{(1R,4S)-4-[3-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)ureido]-1,2,3,4-tetrahydronaphthalen-1-yloxymethyl}pyridin-2-yl)-2-methoxyacetamide
- 1443245-37-1 methanesulfonic acid 3-[3-tert-butyl-5-(3-{(1S,4R)-4-[3-((S)-2-methyl-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl}-ureido)-pyrazol-1-yl]-benzyl ester
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(1R,4S)-4-amino-1,2,3,4-tetrahydronaphthalen-l-ol
