1352122-62-3

Basic information

• Product Name: 3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one
• Synonyms: 3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one
• CAS NO: 1352122-62-3
• Molecular Weight: 462.589
• Mol File: 1352122-62-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one(1352122-62-3)
• EPA Substance Registry System: 3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one(1352122-62-3)

Safety Data

• Hazardous Substances Data: 1352122-62-3(Hazardous Substances Data)

Upstream product

• 3722-44-9 3-hydroxy-7,8,9,10-tetrahydrobenzo[c]chromen-6-one 
• 35386-24-4 1-(2-Methoxyphenyl)piperazine 
• 1578300-98-7 3-(4-bromobutoxy)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one 
• 41302-34-5 2-(methoxycarbonyl)cyclohexanone 
• 1732-08-7 dimethyl 1,7-heptanedioate 
• 111-16-0 heptanedioic acid 

Relevant articles and documents

ALICYCLIC[C] BENZOPYRONE DERIVATIVES AND USES THEREOF

Disclosed are alicyclic[c]benzopyrone derivatives and use thereof. The alicyclic[c]benzopyrone derivatives are compounds represented by formula I or their salts. The present compounds not only significantly improve high activity induced by MK-801, but also effectively improve clambering symptom induced by Apomorphine and do not cause EPS within effective dose. These in vitro targets and in vivo pharmacological models are closely related to diseases of the nervous system caused by dopamine dysfunction, especially schizophrenia. Therefore the present compounds can be used for the treatment of central nervous system diseases, especially schizophrenia. ED50 is lower and effect is stronger in two animal models i.e. high activity induced by MK-801 and clambering symptom induced by Apomorphine, while ED50 is higher and therapeutic index is greater in animal models of catalepsy.