1352166-01-8

Upstream product

• 106-95-6 allyl bromide 
• 130748-67-3 (2S)-N-(4-methylbenzene)-1-sulfonoamido-4-methylpentan-1-ol 
• 7533-40-6 (S)-2-amino-4-methylpentan-1-ol 
• 98-59-9 p-toluenesulfonyl chloride 
• 1220-80-0 (S)-4-methyl-2-(toluene-4-sulfonamido)pentanoic acid 
• 73270-65-2 N-allylated leucine methyl ester 
• 2666-93-5 (S)-Leu-OMe 
• 61-90-5 L-leucine 
• 1352165-99-1 C₁₇H₂₅NO₄S 
• 316363-73-2 (S)-O-(tert-butyldimethylsilyl)-N-(4-methylbenzenesulfonyl)-leucinol 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 

Downstream Products

• 1352166-06-3 C₁₆H₂₄INO₃S 
• 1352166-19-8 C₂₃H₃₂N₂O₂S 
• 1352166-24-5 C₂₃H₃₁IN₂O₂S 
• 1352166-14-3 C₂₃H₃₁NO₅S₂ 

Relevant academic research and scientific papers

Enantio- and Regioselective Palladium(II)-Catalyzed Dioxygenation of (Aza-)Alkenols

An oxidative Pd-catalyzed intra-intermolecular dioxygenation of (aza-)alkenols has been reported, with total regioselectivity. To study the stereoselectivity, different chiral ligands as well as different hypervalent-iodine compounds have been compared. I

Selective 7- endo -Cyclization of 3-Aza-5-alkenols through Oxidative Pd(II)-Catalyzed Olefin Oxyarylation

3-Aza-5-alkenols undergo selective 7- endo - trig cyclization when treated with a catalytic Pd(II) species, CuCl 2 and ArSnBu 3 giving 7-aryl-substituted oxazepanes. The intramolecular alkoxylation occurs with formation of a seven-me

Aryl λ3-Iodane-Mediated 6-exo-trig Cyclization to Synthesize Highly Substituted Chiral Morpholines

A mild and efficient transition metal-free approach has been developed for the synthesis of highly substituted chiral morpholines from alkenols by amino acid-derived iodine(III) reagents via a 6-exo-trig cyclization. The key features of this work include

I2-mediated diversity oriented diastereoselective synthesis of amino acid derived trans-2,5-disubstituted morpholines, piperazines, and thiomorpholines

Diastereoselective trans-2,5-disubstituted amino acids derived diverse morpholines, piperazines and thiomorpholines were prepared in 30 min-1 h with high yields through iodine-mediated 6-exotrig type cyclization from a single common synthetic intermediate. The displacement of iodine with hydride ion gave a methyl substituent at the 2-position of morpholines which provides an additional opportunity for diversity oriented nucleophilic substitution on the rings as well as incorporation of substituents at the 5-position from amino acids constituents.