1352187-22-4

Basic information

• Product Name: C₂₆H₂₇Cl₂NO₇S
• Synonyms: C₂₆H₂₇Cl₂NO₇S
• CAS NO: 1352187-22-4
• Molecular Weight: 568.475
• Mol File: 1352187-22-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₇Cl₂NO₇S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₇Cl₂NO₇S(1352187-22-4)
• EPA Substance Registry System: C₂₆H₂₇Cl₂NO₇S(1352187-22-4)

Safety Data

• Hazardous Substances Data: 1352187-22-4(Hazardous Substances Data)

Upstream product

• 1215080-61-7 (2R)-1-(phenylthio)-3-(tetrahydro-2H-pyran-2-yloxy)propan-2-ol 
• 1215080-64-0 (4S)-3-ethyl 5-(1-(phenylthio)-3-(tetrahydro-2H-pyran-2-yloxy)propan-2-yl) 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 1215080-63-9 (2R)-1-(phenylthio)-3-(tetrahydro-2H-pyran-2-yloxy)propan-2-yl 2-(2,3-dichlorobenzylidene)-3-oxobutanoate 
• 1215080-62-8 (2R)-1-(phenylthio)-3-(tetrahydro-2H-pyran-2-yloxy)propan-2-yl 3-oxobutanoate 

Downstream Products

• 105618-03-9 (S)-Felodipine 

Relevant articles and documents

A facile synthesis of (S)-felodipine

A short and facile synthesis of (S)-felodipine was developed starting from (R)-glycidol as the source of the chiral auxiliary. 2-Hydroxyethyl esters were found to undergo selective transesterification reactions in the presence of other esters. This selective transesterification reaction was applied to the synthesis of (S)-felodipine through selective substitution of the 2-hydroxyethyl group possessing chiral ester with sodium methoxide.