1352347-01-3 Usage
Description
(E)-1-(2-chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one, a chalcone derivative and a type of flavonoid, is a chemical compound with the molecular formula C17H15ClO3. It is characterized by its yellow solid appearance and its solubility in organic solvents, while being insoluble in water. (E)-1-(2-chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one has garnered attention for its potential pharmaceutical properties, which include anti-inflammatory, antioxidant, and anticancer effects. As its specific biological activities and therapeutic applications are still under investigation, it remains a topic of interest for ongoing research within the fields of medicine and pharmacology.
Uses
Used in Pharmaceutical Applications:
(E)-1-(2-chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one is used as a potential therapeutic agent for its anti-inflammatory properties, which may help in reducing inflammation associated with various diseases and conditions.
(E)-1-(2-chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one is also used for its antioxidant capabilities, which can protect cells from damage caused by harmful molecules known as free radicals.
Furthermore, this compound is used in anticancer research due to its potential to exhibit antitumor activity, making it a candidate for the development of novel cancer treatments.
Used in Chemical Research:
In the field of chemical research, (E)-1-(2-chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one serves as a subject for further investigation into its biological activities and possible applications in medicine and pharmacology, contributing to the advancement of knowledge in these areas.
Check Digit Verification of cas no
The CAS Registry Mumber 1352347-01-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,2,3,4 and 7 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1352347-01:
(9*1)+(8*3)+(7*5)+(6*2)+(5*3)+(4*4)+(3*7)+(2*0)+(1*1)=133
133 % 10 = 3
So 1352347-01-3 is a valid CAS Registry Number.
1352347-01-3Relevant articles and documents
The synthesis and synergistic antifungal effects of chalcones against drug resistant Candida albicans
Wang, Yuan-Hua,Dong, Huai-Huai,Zhao, Fei,Wang, Jie,Yan, Fang,Jiang, Yuan-Ying,Jin, Yong-Sheng
supporting information, p. 3098 - 3102 (2016/06/13)
To identify effective and low toxicity synergistic antifungal compounds, 24 derivatives of chalcone were synthesized to restore the effectiveness of fluconazole against fluconazole-resistant Candida albicans. The minimal inhibitory concentration (MIC80) and the fractional inhibitory concentration index (FICI) of the antifungal synergist fluconazole were measured against fluconazole-resistant Candida albicans. This was done via methods established by the clinical and laboratory standards institute (CLSI). Of the synthesized compounds, 2′-hydroxy-4′-methoxychalcone (8) exhibited the most potent in vitro (FICI = 0.007) effects. The structure activity relationship of the compounds are then discussed.
