1352347-01-3 Usage
Uses
Used in Pharmaceutical Applications:
(E)-1-(2-chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one is used as a potential therapeutic agent for its anti-inflammatory properties, which may help in reducing inflammation associated with various diseases and conditions.
(E)-1-(2-chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one is also used for its antioxidant capabilities, which can protect cells from damage caused by harmful molecules known as free radicals.
Furthermore, (E)-1-(2-chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one is used in anticancer research due to its potential to exhibit antitumor activity, making it a candidate for the development of novel cancer treatments.
Used in Chemical Research:
In the field of chemical research, (E)-1-(2-chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one serves as a subject for further investigation into its biological activities and possible applications in medicine and pharmacology, contributing to the advancement of knowledge in these areas.
Check Digit Verification of cas no
The CAS Registry Mumber 1352347-01-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,2,3,4 and 7 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1352347-01:
(9*1)+(8*3)+(7*5)+(6*2)+(5*3)+(4*4)+(3*7)+(2*0)+(1*1)=133
133 % 10 = 3
So 1352347-01-3 is a valid CAS Registry Number.
1352347-01-3Relevant academic research and scientific papers
The synthesis and synergistic antifungal effects of chalcones against drug resistant Candida albicans
Wang, Yuan-Hua,Dong, Huai-Huai,Zhao, Fei,Wang, Jie,Yan, Fang,Jiang, Yuan-Ying,Jin, Yong-Sheng
supporting information, p. 3098 - 3102 (2016/06/13)
To identify effective and low toxicity synergistic antifungal compounds, 24 derivatives of chalcone were synthesized to restore the effectiveness of fluconazole against fluconazole-resistant Candida albicans. The minimal inhibitory concentration (MIC80) and the fractional inhibitory concentration index (FICI) of the antifungal synergist fluconazole were measured against fluconazole-resistant Candida albicans. This was done via methods established by the clinical and laboratory standards institute (CLSI). Of the synthesized compounds, 2′-hydroxy-4′-methoxychalcone (8) exhibited the most potent in vitro (FICI = 0.007) effects. The structure activity relationship of the compounds are then discussed.
Synthesis and cdc25B inhibitory activity evaluation of chalcones
Zhao, Fei,Zhao, Qing-Jie,Zhao, Jing-Xia,Zhang, Da-Zhi,Wu, Qiu-Ye,Jin, Yong-Sheng
, p. 206 - 214 (2013/07/26)
A library of sixty-five chalcones was prepared for screening against the protein phosphatase, cdc25B. From this library, thirteen compounds were found having good inhibitory activity. Two compounds have excellent activity and can be used for the design of
