1352397-33-1

Basic information

• Product Name: 3-Iodo-7-oxide-7-azaindole
• Synonyms: 3-Iodo-7-oxide-7-azaindole
• CAS NO: 1352397-33-1
• Molecular Formula: C7H5IN2O
• Molecular Weight: 260.03
• Mol File: 1352397-33-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Iodo-7-oxide-7-azaindole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Iodo-7-oxide-7-azaindole(1352397-33-1)
• EPA Substance Registry System: 3-Iodo-7-oxide-7-azaindole(1352397-33-1)

Safety Data

• Hazardous Substances Data: 1352397-33-1(Hazardous Substances Data)

Upstream product

• 271-63-6 7-Azaindole 
• 23616-57-1 3-iodo-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 1190322-78-1 6-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine 

Relevant articles and documents

Cu(II)-catalyzed sulfonylation of 7-azaindoles using DABSO as SO2-Source and its mechanistic study

DABSO mediated sulfonylation of iodinated 7-azaindoles was achieved for the first time through sulfonylative Suzuki-Miyaura cross coupling (SMC) reaction under mild conditions giving good yields of sulfonylated 7-azaindole derivatives. Interestingly, control experiments suggest that present method involves in-situ generation of ArSO2 free radical followed by the key steps of SMC reaction. Scope of the reaction was explored with both electronically different and bulky group carrying boronic acids as coupling partner. The sulfonylation is scalable and occurred selectively at iodo group, irrespective of its position on azaindole. Moreover, the proposed mechanism has been supported by electron paramagnetic resonance (EPR) and density functional theory (DFT) calculations.