1352399-71-3Relevant academic research and scientific papers
Conjugation of spermine enhances cellular uptake of the stapled peptide-based inhibitors of p53-Mdm2 interaction
Muppidi, Avinash,Li, Xiaolong,Chen, Jiandong,Lin, Qing
, p. 7412 - 7415 (2011)
We report the first synthesis of the C-terminally spermine-conjugated stapled peptide-based inhibitors of the p53-Mdm2 interaction. Subsequent biological, biophysical and cellular uptake assays with the spermine-conjugated stapled peptides revealed that s
