1352402-69-7Relevant academic research and scientific papers
Regioselective synthesis of 2,8-disubstituted 4-aminopyrido[3,2-d] pyrimidine-6-carboxylic acid methyl ester compounds
Bouscary-Desforges, Gwenaelle,Bombrun, Agnes,Augustine, John Kallikat,Bernardinelli, Gerald,Quattropani, Anna
, p. 243 - 252 (2012)
We report herein the synthesis of 4-amino-2,8-dichloropyrido[3,2-d] pyrimidine derivatives 2 and their regioselective diversification through S NAr and metal-catalyzed cross-coupling reactions. While amination of 2 took place selectively at C-2
