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N-(3-ethynylphenyl)-2-hydroxy-5-nitrobenzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1352440-70-0

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1352440-70-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1352440-70-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,2,4,4 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1352440-70:
(9*1)+(8*3)+(7*5)+(6*2)+(5*4)+(4*4)+(3*0)+(2*7)+(1*0)=130
130 % 10 = 0
So 1352440-70-0 is a valid CAS Registry Number.

1352440-70-0Relevant articles and documents

Nusbiarylins, a new class of antimicrobial agents: Rational design of bacterial transcription inhibitors targeting the interaction between the NusB and NusE proteins

Qiu, Yangyi,Chan, Shu Ting,Lin, Lin,Shek, Tsun Lam,Tsang, Tsz Fung,Zhang, Yufeng,Ip, Margaret,Chan, Paul Kay-sheung,Blanchard, Nicolas,Hanquet, Gilles,Zuo, Zhong,Yang, Xiao,Ma, Cong

, (2019)

Discovery of antibiotics of a novel mode of action is highly required in the fierce battlefield with multi-drug resistant bacterial infections. Previously we have validated the protein-protein interaction between bacterial NusB and NusE proteins as an unp

Synthesis and biological evaluation of N-aryl salicylamides with a hydroxamic acid moiety at 5-position as novel HDAC-EGFR dual inhibitors

Zuo, Miao,Zheng, Yue-Wen,Lu, She-Min,Li, Yan,Zhang, San-Qi

experimental part, p. 4405 - 4412 (2012/09/05)

A novel series of N-aryl salicylamides with a hydroxamic acid moiety at 5-position were synthesized efficiently. Their activities against EGFR kinase and HDACs were evaluated. All compounds displayed inhibitory activity against EGFR and HDACs. The antiproliferative activities of synthesized compounds were evaluated by MTT method against human cancer cell lines A431, A549 and HL-60. Compound 1o showed the most potent inhibitory activity against A431 and A549. Compounds 1k and 1n exhibited higher potency against HL-60 than gefitinib and SAHA. N-Aryl salicylamides with a hydroxamic acid moiety at 5-position is another new HDAC-EGFR dual inhibitors.

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