1352504-89-2

Upstream product

• 130128-70-0 5'-amino-3'-O-(tert-butyldimethylsilyl)-5’-deoxythymidine 
• 23163-86-2 1-chloro-4-isothiocyanato-2-(trifluoromethyl)benzene 
• 1352504-87-0 5-(5'-amino-5'-deoxy-3'-O-tert-butyldimethylsilyl-β-D-thymidin-5'N-yl)-1-(4-chloro-3-trifluoromethylphenyl)tetrazole 
• 1352504-84-7 N-(5'-deoxy-3'-O-tert-butyldimethylsilyl-β-D-thymidin-5'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)thiourea 

Relevant academic research and scientific papers

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase

We report on Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt) inhibitory activities of a series of new 3′- and 5′-modified thymidine analogues including α- and β-derivatives. In addition, several analogues were synthesized in which the 4