135253-20-2

Basic information

• Product Name: 3-Butyl-3-methyl-2-phenylthio-5-pentanolide
• CAS NO: 135253-20-2
• Molecular Weight: 278.415
• Mol File: 135253-20-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Butyl-3-methyl-2-phenylthio-5-pentanolide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butyl-3-methyl-2-phenylthio-5-pentanolide(135253-20-2)
• EPA Substance Registry System: 3-Butyl-3-methyl-2-phenylthio-5-pentanolide(135253-20-2)

Safety Data

• Hazardous Substances Data: 135253-20-2(Hazardous Substances Data)

Upstream product

• 882-33-7 diphenyldisulfane 
• 931-59-9 benzenesulfenyl chloride 
• 89030-23-9 3-Butyl-2-phenylthio-5-pentanolide 
• 94451-06-6 2-(phenylthio)-2-penten-5-olide 
• 89036-08-8 2-(phenylthio)-5-pentanolide 
• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 917-54-4 methyllithium 
• 89030-30-8 3-Butyl-2-phenylthio-2-penten-5-olide 

Relevant articles and documents

An Useful Synthetic Method for 3-Substituted δ-Lactones. Synthesis of (+/-)-Secocrispiolide

2-Phenylthio-2-penten-5-olide (1) acted as a reactive Michael acceptor toward some typical carbon nucleophiles to give 3-substituted 2-phenylthio-5-pentanolides (2) which were convertible both to 3-substituted 5-pentanolides by reductive desulfurization and to 3-substituted 2-penten-5-olides by sulfenic acid syn elimination of the sulfoxides 4 derived from 2.The Pummerer rearrangement of 4 provided 3-substituted 2-phenylthio-2-penten-5-olides and/or 2-hydroxy-2-penten-5-olides. (+/-)-Secocrispiolide was synthesized via the adduct obtained by the Michael reaction of 1 with the Grignard reagent prepared from 2,6-dimethylbenzyl bromide and magnesium.