1352571-48-2

Upstream product

• 108-46-3 recorcinol 
• 68792-12-1 3-isopropoxyphenol 
• 1352571-33-5 2-chloro-5-isopropyl-4-(4-methoxybenzyloxy)pyrimidine 
• 1352571-47-1 2-(3-isopropoxy-5-(4-(methylsulfonyl)phenoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1352571-32-4 1-isopropoxy-3-(4-(methylsulfonyl)phenoxy)benzene 
• 514843-12-0 2,4-dichloro-5-iso-propylpyrimidine 
• 17432-95-0 5-isopropyluracil 

Downstream Products

• 1352570-43-4 2-(3-isopropoxy-5-(4-(methylsulfonyl)phenoxy)phenyl)-5-isopropylpyrimidin-4(3H)-one 

Relevant academic research and scientific papers

2-(3,5-DISUBSTITUTEDPHENYL)PYRIMIDIN-4(3H)-ONE DERIVATIVES

O N NH R3 R2 O R1 168 ABSTRACT The present invention provides a 2-(3,5-disubstitutedphenyl)pyrimidin- 4(3H)-one compound of Formula (I) 5 (I) or a pharmaceutically acceptable salt thereof wherein R 1, R2 and R3 are as defined herein. The compounds of Formula (I) have been found to act as glucokinase activators. Consequently, the compounds of Formula (I) and 10 the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucokinase.