1352572-34-9Relevant academic research and scientific papers
Microwave-assisted synthesis and bioactivity of novel 2,2,4,5- tetrasubstituted 3-dichloroacetyl-1,3-oxazolidines
Fu, Ying,Yang, Lei,Ye, Fei,Gao, Shuang
, p. 2607 - 2613 (2011)
An efficient one-pot synthesis of 2,2,4,5-tetrasubstituted 3-dichloroacetyl-1,3-oxazolidines under microwave irradiation was developed. The intermediate oxazolidines were attained by the reaction of amino alcohol with aldehyde or ketone in refluxing benzene with microwave-assisted cycloaddition, and then the acylation followed with dichloroacetyl chloride and NaOH acting as the attaching acid agent. All the compounds were characterized by IR, 1H-NMR, 13C-NMR and elemental analysis. The preliminary biological test shows that these compounds could protect maize against injury caused by acetochlor to a certain extent.
