1352574-91-4

Usage

Uses

Used in Pharmaceutical Synthesis:
(2R)-2-AMINO-3-(2-FLUOROPHENYL)PROPAN-1-OL is used as a key intermediate in the synthesis of pharmaceuticals for its unique structural features and biological activity, contributing to the development of new drugs with specific therapeutic targets.
Used in Research Chemicals:
In the field of biological and medicinal research, (2R)-2-AMINO-3-(2-FLUOROPHENYL)PROPAN-1-OL serves as a research chemical, aiding scientists in studying various biological processes and mechanisms, potentially leading to advancements in understanding and treating diseases.

Upstream product

• 19883-78-4 (S)-2-fluorophenylalanine 
• 97731-02-7 (R)-2'-fluorophenylalanine 

Relevant academic research and scientific papers

Biosynthesis of Fluorinated Peptaibols Using a Site-Directed Building Block Incorporation Approach

Synthetic biological approaches, such as site-directed biosynthesis, have contributed to the expansion of the chemical space of natural products, making possible the biosynthesis of unnatural metabolites that otherwise would be difficult to access. Such m

ISOINDOLINONE AND PYRROLOPYRIDINONE DERIVATIVES AS AKT INHIBITORS

The present invention provides isoindolinone and pyrrolopyridinone derivatives, as well as their compositions and methods of use, that inhibit the activity of the serine/threonine kinase, Akt, and are useful in the treatment of diseases related to the act

HYDROXYMORPHOLINONE DERIVATIVE AND MEDICINAL USE THEREOF

A compound represented by the following formula (I) wherein R1 and R2 are each a lower alkyl group optionally having substituents, which has a calpain inhibitory activity, or a salt thereof is provided.

Aldehyde derivatives and their use as calpain inhibitors

Aldehyde derivatives with a specific calpain inhibiting activity and a platelet-aggregation inhibiting effect with formula (I) or formula (II): wherein R1 represents an aromatic hydrocarbon group, a heterocyclic group, or a group of-X-R3 in which X represents O,-S(O)m-(m = 0, 1, or 2), and R3 represents an aromatic hydrocarbon group, a heterocyclic group, or an alkyl group; Z represents R?-Y-or R?O-CH(R?)-in which Y represents a 3-to 7-membered nitrogen-containing saturated heterocyclic group, or a single cyclic saturated hydrocarbon group, R? represents an alkyl group, an alkenyl group, an alkynyl group, an acyl group, a sulfonyl group, an alkoxycarbonyl group, a carbamoyl group, or a thiocarbamoyl group, R? represents hydrogen, an alkyl group, or an aromatic hydrocarbon group, and R? represents an acyl group, a carbamoyl group, a thiocarbamoyl group, or an alkyl group; and n is an integer of 1 to 5. wherein R?, R?, R?, and R1? are defined in the specification.