1352626-59-5Relevant articles and documents
Rational modulation of coumarin-hemicyanine platform based on OH substitution for higher selective detection of hypochlorite
Lan, Jin-Shuai,Liu, Li,Zeng, Rui-Feng,Qin, Yan-Hong,Liu, Yun,Jiang, Xiao-Yi,Aihemaiti, Ayinazhaer,Ding, Yue,Zhang, Tong,Ho, Rodney J. Y.
, p. 1219 - 1222 (2020)
To monitor delicate changes of biological HOCl in vivo, a new probe (OH-substituted coumarin-hemicyanine, probe 2) was synthesized for NIR and ratiometric HOCl detection. Selectivity studies indicated that the electron-donating group (OH) substituted on the indolium moiety enhanced the selectivity to detect HOCl. With HOCl, the probe showed a ratiometric fluorescence (I500/I650) with a low detection limit (49.1 nM) and a rapid response (within 2 min). In addition, probe 2 was successfully applied to visualize exogenous and endogenous HOCl in living cells and animals and exhibited a perfect mitochondria target ability. This probe has been further studied as a potential and powerful tool to probe HOCl in arthritis models.
A ratiometric fluorescent probe for rapid and sensitive visualization of hypochlorite in living cells
Zha, Jiayu,Fu, Boqiao,Qin, Caiqin,Zeng, Lintao,Hu, Xichao
, p. 43110 - 43113 (2014)
A ratiometric fluorescent probe for ClO- has been developed based on coumarin-hemicyanine, which displayed a colorimetric and fluorescence response to ClO- with high selectivity, fast response (within 2 min) and an extremely low dete
Rapid, selective, and sensitive fluorometric detection of cyanide anions in aqueous media by cyanine dyes with indolium-coumarin linkages
Shiraishi, Yasuhiro,Nakamura, Masaya,Yamamoto, Kohei,Hirai, Takayuki
, p. 11583 - 11586 (2014)
Cyanine dyes with indolium-coumarin linkages exhibit selective fluorescence enhancement for cyanide anions (CN-) via the nucleophilic interaction of CN- with their indolium carbon atoms. This facilitates rapid (detection time: 1 min) and sensitive (detection limit: 0.4 μM) sensing of CN- in aqueous media.
Fluorescent probe for detecting SO2 as well as synthesis method and application of fluorescent probe
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Paragraph 0040-0041; 0045-47, (2021/04/10)
The invention discloses a fluorescent probe for detecting SO2 as well as a synthesis method and application of the fluorescent probe. The structural formula of the fluorescent probe is shown in the specification. The probe is rapid and simple to synthesize and relatively high in yield. The fluorescent probe A-1 provided by the invention can be subjected to nucleophilic addition reaction with SO2 derivatives, so that the solution is changed into faint yellow from dark purple, can be distinguished by naked eyes, has good selectivity and specificity, has extremely high sensitivity, realizes trace high-sensitivity detection of SO2 and can be applied to real-time detection of a gas additive SO2 in wine; therefore, good development prospects are realized in the field of food safety.