135263-85-3Relevant academic research and scientific papers
Asymmetric Induction in Acyclic Radical Reactions: Enantioselective Syntheses of α-Amino Acids via Carbon-Carbon Bond Forming Radical Reactions.
Hamon, David P. G.,Massy-Westropp, Ralph A.,Razzino, Pasquale
, p. 4183 - 4194 (1995)
The derivative of glycine, 8-phenylmenthyl N-Boc-2-bromoglycinate 1 reacted with allyltri-n-butylstannanes via the corresponding radical 2 by the SH2' mechanism to give (2S) allyl amino acid derivatives with high diastereoselectivity.The reaction of 1 with triphenyl(1,2-propadienyl)stannane and triphenyl(2-propynyl)stannane gave the (2S) allenyl and (2S) propargyl amino acid derivatives respectively also with high diastereoselectivity but by a different mechanism.
Enantioselective Syntheses of α-Amino Acids via Carbon-Carbon Bond Forming Radical Reactions
Hamon, David P. G.,Massy-Westropp, Ralph A.,Razzino, Pasquale
, p. 722 - 724 (2007/10/02)
The derivative of glycine, 8-phenylmenthyl N-Boc-2-bromoglycinate 2 reacts with unsaturated stannanes to give unsaturated amino acid derivatives with high diastereoselectivity.
