1352630-63-7Relevant articles and documents
Metal-free oxidation/C(sp3)iH functionalization of unactivated alkynes using pyridine-N-oxide as the external oxidant
Chen, Dian-Feng,Han, Zhi-Yong,He, Yu-Ping,Yu, Jie,Gong, Liu-Zhu
supporting information, p. 12307 - 12310 (2013/02/22)
Externally yours: 2,3-Dihydroquinolin-4(1H)-ones are obtained in moderate to good yields (40-84 %, see scheme) in a metal-free oxidation/C(sp 3)iH functionalization of unactivated aryl alkynes. 2,6-Dichloropyridine-N-oxide is used as an external oxidant. In the reaction, a Bronsted acid, not a metal, plays a key role in the triple CiC bond activation. Copyright