1352630-66-0

Basic information

• Product Name: 1-(2-bromo-5-methylphenyl)pyrrolidine
• Synonyms: 1-(2-bromo-5-methylphenyl)pyrrolidine
• CAS NO: 1352630-66-0
• Molecular Weight: 240.143
• Mol File: 1352630-66-0.mol

Chemical Properties

• CAS DataBase Reference: 1-(2-bromo-5-methylphenyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-bromo-5-methylphenyl)pyrrolidine(1352630-66-0)
• EPA Substance Registry System: 1-(2-bromo-5-methylphenyl)pyrrolidine(1352630-66-0)

Safety Data

• Hazardous Substances Data: 1352630-66-0(Hazardous Substances Data)

Upstream product

• 110-52-1 1,4-dibromo-butane 
• 53078-85-6 2-bromo-5-methylaniline 

Downstream Products

• 1352630-62-6 (3aR,5S)-ethyl 4-(4-methoxyphenyl)-8-methyl-1,2,3,3a,4,5-hexahydropyrrolo[1,2-a]quinazoline-5-carboxylate 
• 1352630-68-2 ethyl 2-(4-methyl-2-(pyrrolidin-1-yl)phenyl)-2-oxoacetate 
• 1443006-51-6 C₁₆H₂₃NSi 

Relevant articles and documents

Asymmetric sp3 C-H functionalization via a chiral Br?nsted acid-catalyzed redox reaction for the synthesis of cyclic aminals

An organocatalytic asymmetric tandem 1,5-hydride transfer/ring closing reaction of o-aminobenzoketones with anilines to give cyclic aminals in fairly good diastereo- and enantioselectivities.

N-{[2-(PIPERIDIN-1-YL)PHENYL](PHENYL)METHYL}-2-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXA ZIN-7-YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ROR-GAMMA MODULATORS FOR TREATING AUTOIMMUNE DISEASES

The present invention provides e.g. N-{[2-(piperidin-1-yl)phenyl] (phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)acetamide derivatives and related compounds as ROR-gamma modulators for treating e.g. autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases or cholestatic diseases, such as e.g. arthitis and asthma.

Metal-free oxidation/C(sp3)iH functionalization of unactivated alkynes using pyridine-N-oxide as the external oxidant

Externally yours: 2,3-Dihydroquinolin-4(1H)-ones are obtained in moderate to good yields (40-84 %, see scheme) in a metal-free oxidation/C(sp 3)iH functionalization of unactivated aryl alkynes. 2,6-Dichloropyridine-N-oxide is used as an external oxidant. In the reaction, a Bronsted acid, not a metal, plays a key role in the triple CiC bond activation. Copyright