135265-46-2

Upstream product

• 135265-41-7 Toluene-4-sulfonic acid (2R,3R)-2-hydroxy-4-(4-methoxy-benzyloxy)-3-methyl-butyl ester 
• 135265-40-6 (2R,3R)-4-(4-Methoxy-benzyloxy)-3-methyl-butane-1,2-diol 
• 135265-42-8 (R)-2-[(R)-2-(4-Methoxy-benzyloxy)-1-methyl-ethyl]-oxirane 
• 135265-36-0 (2R,3S,8R,9R)-9-Benzyloxymethoxy-1-(4-methoxy-benzyloxy)-2-methyl-8-(tetrahydro-pyran-2-yloxy)-dec-5-yn-3-ol 

Downstream Products

• 135265-48-4 Acetic acid 2-[(2R,3R)-3-benzyloxymethoxy-2-(tetrahydro-pyran-2-yloxy)-butyl]-5-[(R)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-furan-3-yl ester 
• 135265-37-1 Acetic acid 2-((2R,3R)-3-benzyloxymethoxy-2-hydroxy-butyl)-5-[(R)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-furan-3-yl ester 
• 135265-38-2 (R)-5-(4-Methoxy-benzyloxy)-4-methyl-3-oxo-pentanoic acid (1R,2R)-2-benzyloxymethoxy-1-carboxymethyl-propyl ester 
• 135265-47-3 2-[(2R,3R)-3-Benzyloxymethoxy-2-(tetrahydro-pyran-2-yloxy)-butyl]-5-[(R)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-furan-3-one 

Relevant academic research and scientific papers

SYNTHETIC STUDIES ON APLYSIATOXIN. INTRAMOLECULAR ESTER FORMATION FROM 3-ACETOXYFURAN DERIVATIVE VIA OXIDATIVE RING OPENING REACTION.

Two steps synthesis of 3-acetoxyfuran derivative (4) from acetylene derivative (3) and the conversion of 4 to (3R,4R)-3,4-dihydroxypentanoic acid derivative (5) are described.