1352662-77-1

Basic information

• Product Name: (cycloheptylethynyl)triisopropylsilane
• Synonyms: (cycloheptylethynyl)triisopropylsilane
• CAS NO: 1352662-77-1
• Molecular Weight: 278.553
• Mol File: 1352662-77-1.mol

Chemical Properties

• CAS DataBase Reference: (cycloheptylethynyl)triisopropylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (cycloheptylethynyl)triisopropylsilane(1352662-77-1)
• EPA Substance Registry System: (cycloheptylethynyl)triisopropylsilane(1352662-77-1)

Safety Data

• Hazardous Substances Data: 1352662-77-1(Hazardous Substances Data)

Upstream product

• 2404-35-5 cycloheptyl bromide 
• 159862-82-5 ((triisopropylsilyl)ethynyl)magnesium bromide 
• 2453-46-5 cycloheptyl chloride 

Relevant articles and documents

Bisphosphine compd., and Bisphosphine compound and a transition metal catalyst, and method of manufacturing the same (by machine translation)

PROBLEM TO BE SOLVED: To provide a bisphosphine compound with a new bidentate phosphine ligand having a highly bulky substituent group on a phosphorus atom, which enables highly efficient and highly selective progress in various organic synthesis reactions, especially, cross coupling reaction, and a transition metal catalyst using the bisphosphine compound as a ligand, and a method for manufacturing them.SOLUTION: There are provided a bisphosphine compound represented by general formula (A) or general formula (B) and a transition metal catalyst using the bisphosphine compound as a ligand, and a method for manufacturing them.

Iron-catalyzed Suzuki-Miyaura coupling reaction of unactivated alkyl halides with lithium alkynylborates

A Suzuki-Miyaura coupling reaction between unactivated alkyl halides and lithium alkynylborates was performed using an iron-bisphosphine catalyst. The reaction shows high chemoselectivity and is applicable to a broad scope of substrates bearing electrophilic functional groups. A radical probe experiment using cyclopropylmethyl bromide was conducted to investigate the nature of the intermediate in the reaction, showing that an alkyl radical species is generated from the alkyl halide substrate.