1352748-49-2Relevant academic research and scientific papers
Enantioselective gold(I)-catalyzed intramolecular (4+3) cycloadditions of allenedienes
Alonso, Isaac,Faustino, Helio,Lopez, Fernando,Mascarenas, Jose L.
, p. 11496 - 11500 (2012/01/12)
Allene-tethered dienes (1) undergo an intramolecular and highly enantioselective (4+3) cycloaddition when treated with suitable chiral phosphoramidite/gold(I) catalysts (see scheme; Ar=9-anthracenyl). The reactions provide synthetically relevant [5.3.0] and [5.4.0] fused bicyclic systems 2 with good yields, complete diastereocontrol, and excellent enantioselectivities.
