1352801-48-9Relevant academic research and scientific papers
Complementary regioselectivity in Rh(III)-catalyzed insertions of potassium vinyltrifluoroborate via C-H activation: Preparation and use of 4-trifluoroboratotetrahydroisoquinolones
Presset, Marc,Oehlrich, Daniel,Rombouts, Frederik,Molander, Gary A.
, p. 1528 - 1531 (2013/06/27)
Potassium vinyltrifluoroborate was found to be an efficient partner with benzamide derivatives for Rh(III)-catalyzed annulations. 4- Trifluoroboratotetrahydroisoquinolones were generated under mild conditions, affording a regioisomerically complementary substitution pattern to other alkenes in related reactions. These new boron-containing building blocks were derivatized by N-arylations, retaining the boron substituent for further elaboration.
Rh[III]-catalyzed direct C-H amination using N -chloroamines at room temperature
Grohmann, Christoph,Wang, Honggen,Glorius, Frank
supporting information; experimental part, p. 656 - 659 (2012/03/08)
An efficient Rh(III)-catalyzed direct C-H amination of N-pivaloyloxy benzamides with N-chloroamines proceeding at room temperature was achieved. The versatile directing group allows for selective mono- and diamination and can be readily converted to give valuable benzamide or aminoaniline derivatives. Mechanistic studies have been carried out to elucidate the reaction pathway.
