1352802-83-5

Upstream product

• 420-04-2 CYANAMID 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 1352803-18-9 4-fluoro-N,N-bis(4-methoxybenzyl)-7-(trimethylsilyl)isoquinolin-3-amine 
• 1417213-10-5 C₂₅H₂₂FIN₂O₂ 
• 1352803-26-9 5-fluoro-N,N-bis(4-methoxybenzyl)-7-(trimethylsilyl)isoquinolin-3-amine 
• 1417213-15-0 C₂₅H₂₂FIN₂O₂ 
• 1417212-74-8 C₂₈H₃₂N₂O₂Si 
• 1417212-72-6 C₃₂H₄₂LiN₃O₂Si 
• 1417213-07-0 C₃₂H₄₁FLiN₃O₂Si 

Relevant academic research and scientific papers

METHODS FOR PREPARING ISOQUINOLINES

Provided herein are novel synthetic methods of making isoquinolines comprising coupling a metalated N-(2-methylbenzylidene)amine with a nitrile, followed by cyclization, to provide a substituted isoquinoline compound. This new methodology for preparing is

A versatile synthesis of substituted isoquinolines

Lithiated o-tolualdehyde tert-butylimines were shown to condense with nitriles to form eneamido anion intermediates that were trapped in situ with various electrophiles, thus affording a diverse array of highly substituted isoquinolines, many of which are

6-Substituted pyridoindolone derivatives, production and therapeutic use thereof

Compounds of formula: and pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1, R2, R3, R4, and R5, have the meanings given in the description; pharmaceutical compositions comprising said compounds; and processes for preparing said compounds and methods of use thereof.