1352809-50-7Relevant academic research and scientific papers
Discovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones
Van Der Linden, Wouter A.,Willems, Lianne I.,Shabaneh, Tamer B.,Li, Nan,Ruben, Mark,Florea, Bogdan I.,Van Der Marel, Gijs A.,Kaiser, Markus,Kisselev, Alexei F.,Overkleeft, Herman S.
, p. 181 - 194 (2012)
Syringolins, a class of natural products, potently and selectively inhibit the proteasome and show promising antitumour activity. To gain insight in the mode of action of syringolins, the ureido structural element present in syringolins is incorporated in
