1352831-40-3

Basic information

• Product Name: 2-(4-dimethylamino-1,8-naphthalimido)ethyl isocyanide
• CAS NO: 1352831-40-3
• Molecular Weight: 293.325
• Mol File: 1352831-40-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-dimethylamino-1,8-naphthalimido)ethyl isocyanide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-dimethylamino-1,8-naphthalimido)ethyl isocyanide(1352831-40-3)
• EPA Substance Registry System: 2-(4-dimethylamino-1,8-naphthalimido)ethyl isocyanide(1352831-40-3)

Safety Data

• Hazardous Substances Data: 1352831-40-3(Hazardous Substances Data)

Upstream product

• 77976-79-5 4-(N,N-dimethylamino)-1,8-naphthalic anhydride 
• 81-86-7 4-bromo-1,8-naphthalenedicarboxylic anhydride 
• 81-84-5 1,8-Naphthalic anhydride 
• 1352831-39-0 2-(4-dimethylamino-1,8-naphthalimido)ethylformamide 

Downstream Products

• 1352831-60-7 tert-butyl 2-((4S,7S,10S,12aS,17R,17aS)-4-benzyl-17-((2-(6-(dimethylamino)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl)carbamoyl)-10-isopropyl-3,6,9,12-tetraoxohexadecahydro-1H-azirino[1,2-a]pyrrolo[1,2-d][1,4,7,10,13]pentaazacyclopentadecin-7-yl)acetate 
• 1352831-42-5 (3S,5R,6S)-3-benzyl-N-(2-(6-(dimethylamino)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl)-2-oxo-1,4-diazabicyclo[4.1.0]heptane-5-carboxamide 
• 1352831-52-7 (4R,6aS,11R,11aS)-4-benzyl-N-(2-(6-(dimethylamino)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl)-3,6-dioxodecahydro-1H-azirino[1,2-a]pyrrolo[1,2-d][1,4,7]triazonine-11-carboxamide 
• 1352831-51-6 (4S,6aS,11R,11aS)-4-benzyl-N-(2-(6-(dimethylamino)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl)-3,6-dioxodecahydro-1H-azirino[1,2-a]pyrrolo[1,2-d][1,4,7]triazonine-11-carboxamide 
• 1352831-50-5 (1S,4S,6aR,11S,11aR)-4-(4-(tert-butoxy)benzyl)-N-(2-(6-(dimethylamino)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl)-1-isobutyl-3,6-dioxodecahydro-1H-azirino[1,2-a]pyrrolo[1,2-d][1,4,7]triazonine-11-carboxamide 
• 1352831-57-2 (1S,4S,7S,9aR,14S,14aR)-7-benzyl-N-(2-(6-(dimethylamino)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl)-1-isobutyl-4-methyl-3,6,9-trioxotetradecahydroazirino[1,2-a]pyrrolo[1,2-d][1,4,7,10]tetraazacyclododecine-14-carboxamide 

Relevant articles and documents

Solvatochromic reagents for multicomponent reactions and their utility in the development of cell-permeable macrocyclic peptide vectors

Sensitive scaffolds: An isocyanide equipped with an environment-sensitive fluorophore was used to synthesize peptide macrocycles. The photophysical properties of the product macrocycles are sensitive to both peptide sequence and configuration. A mitochondria-penetrating peptide was constrained within a cyclic peptide framework and showed increased uptake and localization relative to a linear control (see scheme). Copyright