1352834-90-2

Upstream product

• 5318-27-4 6-amino-1H-indole 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 135855-61-7 6-N-methylaminoindole 
• 1613417-29-0 (E)-tert-butyl 6-(4-cyclohexyl-2-((methylcarbamoyl)thio)but-3-en-2-yl)-1H-indole-1-carboxylate 
• 1613417-12-1 (S)-(E)-S-4-cyclohexylbut-3-en-2-yl 1H-indol-6-yl(methyl)carbamothioate 
• 1613417-11-0 (E)-S-4-cyclohexylbut-3-en-2-yl 1H-indol-6-yl(methyl)carbamothioate 
• 1613417-10-9 (S)-(E)-tert-butyl 6-((((4-cyclohexylbut-3-en-2-yl)thio)carbonyl)(methyl)amino)-1H-indole-1-carboxylate 
• 1613417-09-6 (E)-tert-butyl 6-((((4-cyclohexylbut-3-en-2-yl)thio)carbonyl)(methyl)amino)-1H-indole-1-carboxylate 
• 1613416-97-9 (R)-(E)-tert-butyl 6-(4-cyclohexyl-2-mercaptobut-3-en-2-yl)-1H-indole-1-carboxylate 
• 1613416-96-8 (E)-tert-butyl 6-(4-cyclohexyl-2-mercaptobut-3-en-2-yl)-1H-indole-1-carboxylate 
• 1613416-83-3 (E)-tert-butyl 6-(2-(allylthio)-4-cyclohexylbut-3-en-2-yl)-1H-indole-1-carboxylate 
• 1613417-30-3 (S)-(E)-tert-butyl 6-(4-cyclohexyl-2-((methylcarbamoyl)thio)but-3-en-2-yl)-1H-indole-1-carboxylate 
• 1352834-98-0 4-(2-fluorophenyl)-7-(methylsulfonamido)-9H-pyrido[3,4-b]indole-1-carboxamide 
• 1352834-97-9 4-(2-fluorophenyl)-7-(tetrahydro-2H-pyran-4-ylamino)-9H-pyrido[3,4-b]indole-1-carboxamide 
• 1352834-95-7 4-(2-fluorophenyl)-7-(isonicotinamido)-9H-pyrido[3,4-b]indole-1-carboxamide 
• 1352834-96-8 C₂₆H₁₉FN₄O₃ 

Relevant academic research and scientific papers

Dihydrothiophenes containing quaternary stereogenic centres by sequential stereospecific rearrangements and ring-closing metathesis

Stereospecific [3,3]-sigmatropic rearrangement of O-substituted thiocarbamate derivatives of enantiopure allylic alcohols provides allylic thiocarbamates as single enantiomers. Intramolecular arylation by rearrangement of their allyllithium derivatives provides allylic tertiary thiols. Allylation and ring-closing metathesis gives 2,5-dihydrothiophenes containing sulfur-bearing quaternary centres. This journal is the Partner Organisations 2014.

CARBOLINE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS

Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, formula (I) are useful as kinase modulators, including Btk modulation.