1352945-96-0

Basic information

• Product Name: (R)-3-benzyl-3-(phenylamino)indolin-2-one
• Synonyms: (R)-3-benzyl-3-(phenylamino)indolin-2-one
• CAS NO: 1352945-96-0
• Molecular Weight: 314.387
• Mol File: 1352945-96-0.mol

Chemical Properties

• CAS DataBase Reference: (R)-3-benzyl-3-(phenylamino)indolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-benzyl-3-(phenylamino)indolin-2-one(1352945-96-0)
• EPA Substance Registry System: (R)-3-benzyl-3-(phenylamino)indolin-2-one(1352945-96-0)

Safety Data

• Hazardous Substances Data: 1352945-96-0(Hazardous Substances Data)

Upstream product

• 1310861-66-5 (R)-3-benzyl-3-(hydroxy(phenyl)amino)indolin-2-one 
• 1398681-59-8 3-benzyl-3-bromoindolin-2-one 
• 62-53-3 aniline 

Relevant articles and documents

Construction of 3-amino-2-oxindoles by direct amination of aniline or α-amino-acid derivatives to 3-bromooxindoles

The asymmetric amination of anilines to 3-bromooxindoles was developed in the presence of a bis(oxazoline)-Ni(dppp)Cl2complex, to provide enantiomerically enriched 3-amino-2-oxindoles with quaternary stereocenters in up to 90% yield with 92:8 er. Simultaneously, direct stereoselective amination of α-amino-acid methyl esters to 3-bromooxindoles was also accomplished without any catalysts, which furnished the 3-amino-2-oxindole derivatives in high yields with moderate diastereoselectivities.

Asymmetric hydroxyamination of oxindoles catalyzed by chiral bifunctional tertiary amine thiourea: Construction of 3-amino-2-oxindoles with quaternary stereocenters

Chiral bifunctional tertiary amine thiourea was applied to catalyze the asymmetric hydroxyamination of 3-subsituted oxindoles with nitrosobenzene to construct 3-amino-2-oxindoles with quaternary stereocenters in good yields (up to 91%) and enantioselectiv