135297-27-7Relevant articles and documents
4-Substituted trinems as broad spectrum β-lactamase inhibitors: Structure-based design, synthesis, and biological activity
Plantan, Ivan,Seli?, Lovro,Mesar, Toma?,Anderluh, Petra ?tefani?,Oblak, Marko,Pre?elj, Andrej,Hesse, Lars,Andreja?i?, Miha,Vilar, Mateja,Turk, Du?an,Kocijan, Andrej,Prevec, Tadeja,Vilfan, Gregor,Kocjan, Darko,?opar, Anton,Urleb, Uro?,Solmajer, Tom
, p. 4113 - 4121 (2007)
A wide variety of pathogens have acquired antimicrobial resistance as an inevitable evolutionary response to the extensive use of antibacterial agents. In particular, one of the most widely used antibiotic structural classes is the β-lactams, in which the
