135299-52-4Relevant academic research and scientific papers
SYNTHETIC APPLICATIONS OF 2-(1,3-DITHIAN-2-YL)INDOLES. III. A NEW ROUTE TO TETRACYCLIC INTERMEDIATES IN THE SYNTHESIS OF ASPIDOSPERMA INDOLE ALKALOIDS
Troin, Yves,Diez, Anna,Bettiol, Jean-Luc,Rubiralta, Mario,Grierson, David S.,Husson, Henri-Philippe
, p. 663 - 668 (2007/10/02)
The synthesis of tetracyclic framework of Aspidosperma alkaloids has been achieved via allylamine-enamine isomerization using (Ph3P)RhCl in hot aqueous acetonitrile of the 1,2,5,6-tetrahydro-3-(indolylethyl)pyridine (13) which in turn was obtained by Raney nickel desulfurization of the corresponding 2-(1,3-dithian-2-yl)indole (5a).
