1353001-08-7Relevant articles and documents
Bronsted acid catalyzed α-alkylation of aldehydes with diaryl methyl alcohols
Xing, Chong,Sun, Hui,Zhang, Junmin,Li, Guohui,Chi, Yonggui Robin
, p. 12272 - 12275 (2011)
A proton does the two jobs: Bronsted acids alone catalyze the α-alkylation of aldehydes with diaryl alcohols. In this type of transformation, the acid-catalysis approach offers a broader substrate scope compared to the previously used enamine catalysis methods. The acid plays two important roles: one is to mediate the alcohol dehydration for carbocation formation; the other is to accelerate the rate-determining aldehyde enolization (see scheme). Copyright
Direct α-alkylation of aldehydes by bronsted-acid catalysis
Zhu, Xiangrong,Wang, Ting,Guo, Qixiang
supporting information; experimental part, p. 15 - 18 (2012/03/08)
A Bronsted acid catalyzed direct alkylation reaction of aldehydes was described. The 3,5-dinitrobenzoic acid promoted the reaction between aldehydes and diarylmethanols to afford the corresponding alkylation products with middle to high yields (up to 91%