1353011-89-8

Basic information

• Product Name: DNP-PEG2-acid
• Synonyms: DNP-PEG2-acid;DNP-PEG2-COOH
• CAS NO: 1353011-89-8
• Molecular Formula: C13H17N3O8
• Molecular Weight: 343.28938
• Mol File: 1353011-89-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 573.7±50.0 °C(Predicted)
• Appearance: /
• Density: 1.436±0.06 g/cm3(Predicted)
• PKA: 4.28±0.10(Predicted)
• CAS DataBase Reference: DNP-PEG2-acid(CAS DataBase Reference)
• NIST Chemistry Reference: DNP-PEG2-acid(1353011-89-8)
• EPA Substance Registry System: DNP-PEG2-acid(1353011-89-8)

Safety Data

• Hazardous Substances Data: 1353011-89-8(Hazardous Substances Data)

Usage

Description

DNP-PEG2-acid is a PEG (polyethylene glycol) linker that features a DNP (2,4-dinitrophenol) group and a carboxylic acid moiety. This versatile molecule is designed for various biological applications, including ion transport across membranes. The terminal carboxylic acid group can readily react with primary amines in the presence of EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide) and HATU (1-(6-hexanoyloxyhexyl)-1H-benzotriazole) to form stable amide bonds. The hydrophilic PEG linker significantly enhances the water solubility of the compound in aqueous media, making it suitable for a wide range of applications.

Uses

Used in Pharmaceutical Industry:
DNP-PEG2-acid is used as a molecular building block for the development of novel pharmaceutical compounds. Its ability to form stable amide bonds with primary amines allows for the creation of diverse drug candidates with improved water solubility and bioavailability.
Used in Drug Delivery Systems:
In the field of drug delivery, DNP-PEG2-acid serves as a versatile linker for the conjugation of therapeutic agents to targeting moieties or other functional groups. This enhances the specificity and efficacy of drug delivery, potentially reducing side effects and improving patient outcomes.
Used in Diagnostics:
DNP-PEG2-acid can be utilized in the development of diagnostic tools, such as imaging agents or biosensors, due to its compatibility with biological systems and its ability to form stable covalent bonds.
Used in Biochemical Research:
As a research tool, DNP-PEG2-acid can be employed in the synthesis of bioconjugates, protein labeling, and the development of new biomolecular probes for studying cellular processes and interactions.
Used in Cosmetics Industry:
In the cosmetics industry, DNP-PEG2-acid can be used as a component in the formulation of skincare products, where its hydrophilic nature and ability to enhance solubility can improve the performance and bioavailability of active ingredients.
Used in Environmental Applications:
DNP-PEG2-acid may also find use in environmental applications, such as the development of biodegradable materials or the creation of water-soluble complexes for the removal of pollutants from aqueous systems.