1353020-85-5Relevant academic research and scientific papers
Chemical compounds
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Page 11, (2008/06/13)
Compounds of the general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents. 1
2-Hydroxypropyl Nortadalafil is a derivative of Tadalafil (T004500), a phosphodiesterase 5 inhibitor commonly used for the treatment of erectile dysfunction. 2-Hydroxypropyl Nortadalafil possesses structural modifications that may enhance its pharmacological properties or target specific applications.
1353020-85-5
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Basic information
- Product Name: 2-Hydroxypropyl Nortadalafil
- Synonyms: 2-Hydroxypropyl Nortadalafil;YGRCGCUDAOLEEX-QMWSHBGFSA-N
- CAS NO:1353020-85-5
- Molecular Formula: C24H23N3O5
- Molecular Weight: 433.45652
- EINECS: N/A
- Product Categories: Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File: 1353020-85-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 731.3±60.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.51±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: Refrigerator
- Solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
- PKA: 14.47±0.20(Predicted)
- CAS DataBase Reference: 2-Hydroxypropyl Nortadalafil(CAS DataBase Reference)
- NIST Chemistry Reference: 2-Hydroxypropyl Nortadalafil(1353020-85-5)
- EPA Substance Registry System: 2-Hydroxypropyl Nortadalafil(1353020-85-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1353020-85-5(Hazardous Substances Data)
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1353020-85-5 Usage
Uses
Used in Pharmaceutical Industry:2-Hydroxypropyl Nortadalafil is used as a therapeutic agent for the treatment of erectile dysfunction. As a derivative of Tadalafil, it functions as a phosphodiesterase 5 inhibitor, enhancing blood flow to the penis and facilitating an erection in response to sexual stimulation.
Additionally, due to its structural modifications, 2-Hydroxypropyl Nortadalafil may have potential applications in other areas of medicine, such as pulmonary arterial hypertension or benign prostatic hyperplasia. However, further research and clinical trials would be necessary to establish its efficacy and safety in these contexts.
Check Digit Verification of cas no
The CAS Registry Mumber 1353020-85-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,3,0,2 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.Calculate Digit Verification of CAS Registry Number 1353020-85:
(9*1)+(8*3)+(7*5)+(6*3)+(5*0)+(4*2)+(3*0)+(2*8)+(1*5)=115
115 % 10 = 5
So 1353020-85-5 is a valid CAS Registry Number.
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2-Hydroxypropyl Nortadalafil
