1353055-00-1Relevant articles and documents
Synthesis and antimycobacterial activity of novel amino alcohols containing central core of the anti-HIV drugs lopinavir and ritonavir
Gomes, Claudia R.B.,Moreth, Marcele,Cardinot, Danielle,Kopke, Valquiria,Cunico, Wilson,da Silva Lourenco, Maria Cristina,de Souza, Marcus V.N.
experimental part, p. 1031 - 1034 (2012/04/04)
Eleven new amino alcohol derivatives have been synthesized from reactions of lopinavir intermediate and heteroaromatic aldehyde in good yields. These compounds, the antiretrovirals (lopinavir and ritonavir) and lopinavir key intermediate were evaluated as