135306-45-5

Basic information

• Product Name: 3',5'-Difluoropropiophenone
• Synonyms: 3',5'-DIFLUOROPROPIOPHENONE;3,5-DIFLUOROPROPIOPHENONE;3',5'-Difluoropropiophenone 97%;3',5'-Difluoropropiophenone97%;3,5-DIFLUOROPROPIOPHENOL;1-(3,5-difluorophenyl)propan-1-one
• CAS NO: 135306-45-5
• Molecular Formula: C₉H₈F₂O
• Molecular Weight: 170.16
• EINECS: -0
• Product Categories: Aromatic Propiophenones (substituted);Miscellaneous
• Mol File: 135306-45-5.mol

Chemical Properties

• Melting Point: 25 °C
• Boiling Point: 82°C 10mm
• Flash Point: 82°C/10mm
• Appearance: /
• Density: 1.166 g/cm³
• Vapor Pressure: 0.513mmHg at 25°C
• Refractive Index: 1.472
• Storage Temp.: Inert atmosphere,Room Temperature
• BRN: 7422838
• CAS DataBase Reference: 3',5'-Difluoropropiophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5'-Difluoropropiophenone(135306-45-5)
• EPA Substance Registry System: 3',5'-Difluoropropiophenone(135306-45-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-36/37
• HazardClass: IRRITANT
• Hazardous Substances Data: 135306-45-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3',5'-Difluoropropiophenone is utilized as an intermediate in the synthesis of various drugs and pharmaceuticals, playing a crucial role in the development of new medications.
Used in Organic Synthesis:
It serves as a building block in organic synthesis, enabling the creation of more complex chemical compounds for a range of applications.
Used in Medicinal Chemistry and Drug Discovery:
3',5'-Difluoropropiophenone is recognized for its potential applications in medicinal chemistry and drug discovery, making it a significant chemical for research and development within the pharmaceutical field.

InChI:InChI=1/C9H8F2O/c1-6(12)2-7-3-8(10)5-9(11)4-7/h3-5H,2H2,1H3

Upstream product

• 455-40-3 3,5-difluorobenzoic acid 
• 874889-34-6 3,5-difluoro-N-methoxy-N-methylbenzamide 
• 2386-64-3 ethylmagnesium chloride 
• 129714-97-2 3,5-difluorobenzoyl chloride 
• 64248-63-1 3,5-difluorobenzonitrile 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 135306-46-6 2-bromo-3',5'-difluoropropiophenone 
• 1440663-89-7 (E)-1-(3,5-difluorophenyl)-3-(5-methylthiophen-2-yl)prop-2-en-1-one 
• 878571-98-3 1-(3,5-difluorophenyl)propan-1-ol 
• 1428228-99-2 C₁₃H₁₂F₂O₄ 
• 1428229-06-4 C₁₄H₁₄F₂N₂O₂ 
• 1428228-52-7 C₁₈H₁₆F₂N₄O 

Relevant articles and documents

(2S,3S,5R)-2-(3,5-difluorophenyl)-3,5-dimethyl-2-morpholinol: a novel antidepressant agent and selective inhibitor of norepinephrine uptake.

(2S,3S,5R)-2-(3,5-difluorophenyl)-3,5-dimethyl-2-morpholinol: a novel antidepressant agent and selective inhibitor of norepinephrine uptake.

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