135307-53-8Relevant academic research and scientific papers
Synthesis and anti-tuberculosis activity of N-aryl-C-nitroazoles
Walczak, Krzysztof,Gondela, Andrzej,Suwiński, Jerzy
, p. 849 - 853 (2004)
Twelve N-aryl derivatives of 4-nitroimidazole, 2-methyl-4-nitroimidazole, 4-nitropyrazole or 3-nitro-1,2,4-triazole have been synthesized either by a degenerated ring transformation reaction of 1,4-dinitroimidazoles with 4-substituted anilines or by a condensation of fluoronitrobenzenes with salts prepared from C-nitro-1H-azoles and 1,8-diazabicyclo[5.4.0]-7-undecene. The Tuberculosis Antimicrobial Acquisition and Coordinating Facility has provided anti-mycobacterial data concerning inhibition activity of 12 compounds.
