135308-87-1

Basic information

• Product Name: meso-3,5-Diacetoxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptane
• CAS NO: 135308-87-1
• Molecular Weight: 460.524
• Mol File: 135308-87-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: meso-3,5-Diacetoxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptane(CAS DataBase Reference)
• NIST Chemistry Reference: meso-3,5-Diacetoxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptane(135308-87-1)
• EPA Substance Registry System: meso-3,5-Diacetoxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptane(135308-87-1)

Safety Data

• Hazardous Substances Data: 135308-87-1(Hazardous Substances Data)

Upstream product

• 1333233-89-8 C₃₉H₄₂O₈ 

Downstream Products

• 135308-89-3 Acetic acid 4-[(3S,5R)-3,5-diacetoxy-7-(4-acetoxy-3-methoxy-phenyl)-heptyl]-2-methoxy-phenyl ester 
• 153381-09-0 (3R,5S)-3,5-Dihydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptane 

Relevant articles and documents

Stereo-conserved synthesis of syn-diarylheptanoids, active principles of Zingiber, starting from d-glucose

A highly efficient and stereo-controlled synthetic strategy has been developed to access syn-diarylheptanoids, for example, 2, 3, 4, and 5b starting from d-glucose as a chiral pool. The 3-(R), 5-(S)-syn-diol stereochemistry present in these heptanoids was obtained after conserving C2 and C4 stereochemistry of d-glucose during the course of synthetic transformation. The key features of this synthetic strategy include: (i) conversion of d-glucose to a known chiral template 6 armored with the required 1,3-syn-diol stereochemistry as well as two terminal aldehyde functionalities for building up customized 'diaryl wings'; (ii) conversion of 6 to 7 via an initial Wittig olefination at the C5-aldehyde; (iii) use of the hemiacetal 7 as a common intermediate to obtain the individual heptanoids via a second Wittig reaction at its anomeric center using appropriately chosen ylides.