135311-72-7

Basic information

• Product Name: 1-phenyl-2,2,2-trifluoroethyl α-cyano-α-fluorophenylacetate
• CAS NO: 135311-72-7
• Molecular Weight: 337.273
• Mol File: 135311-72-7.mol

Chemical Properties

• CAS DataBase Reference: 1-phenyl-2,2,2-trifluoroethyl α-cyano-α-fluorophenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-2,2,2-trifluoroethyl α-cyano-α-fluorophenylacetate(135311-72-7)
• EPA Substance Registry System: 1-phenyl-2,2,2-trifluoroethyl α-cyano-α-fluorophenylacetate(135311-72-7)

Safety Data

• Hazardous Substances Data: 135311-72-7(Hazardous Substances Data)

Upstream product

• 340-04-5 1-phenyl-2,2,2-trifluoromethylethanol 
• 135311-67-0 (S)-(-)-α-cyano-α-fluorophenylacetyl chloride 
• 135311-64-7 (S)-(-)-α-cyano-α-fluorophenylacetic acid 
• 10549-15-2 N-<(R)-1-phenylethyl>benzoylformaide 
• 145165-64-6 α-cyano-α-fluorophenylacetyl chloride 
• 135339-46-7 (S)-α-cyano-α-fluoro-N-<(R)-1-phenylethyl>phenylacetamide 
• 135311-66-9 C₁₇H₁₄FN₃O₂ 

Relevant articles and documents

Chemistry of novel compounds with multifunctional carbon structure. 8. Application of the α-cyano-α-fluorophenylacetic acid (CFPA) method to the enantiomeric excess determination of some hindered alcohols in asymmetric and natural product syntheses

The reaction of CFPA chloride (2b) with pinacolyl alcohol was found to proceed more than 500 times faster than that of MTPA chloride (1b) suggesting that the CFPA method induces potentially much less kinetic resolution than the widely used MTPA method in

The Remarkably High Reactivity of α-Cyano-α-fluorophenylacetyl Chloride (CFPA-Cl) towards Hindered Nucleophiles in Enantiomeric Excess Determination

The reaction of PhCF(CN)COCl 2b with 3,3-dimethylbutal-2-ol 5 was found to proceed more than 500 times faster than that of PhCCF3(OMe)COCl (MTPA-Cl) 1b, suggesting that the CFPA method should potentially lead to much less kinetic resolution than the curre