1353154-33-2Relevant articles and documents
A two-step continuous-flow synthesis of n-(2-aminoethyl)acylamides through ring-opening/hydrogenation of oxazolines
Gutmann, Bernhard,Roduit, Jean-Paul,Roberge, Dominique,Kappe, C. Oliver
, p. 13146 - 13150 (2011)
Harnessing hydrazoic acid in flow! 2-Oxazolines can be ring-opened in a very efficient manner by treatment with in situ generated hydrazoic acid. Despite the toxic and explosive nature of hydrazoic acid, this process can be conducted safely in a continuou