1353155-79-9Relevant academic research and scientific papers
Expeditious diastereoselective construction of a thiochroman skeleton via a cinchona alkaloid-derived catalyst
Du, Zhiyun,Zhou, Chenggang,Gao, Yaojun,Ren, Qiao,Zhang, Kun,Cheng, Hansong,Wang, Wei,Wang, Jian
supporting information; experimental part, p. 36 - 39 (2012/01/06)
An example of diastereoselective and enantioselective synthesis of thiochroman derivatives through a sulfa-Michael-Michael cascade sequence is disclosed. This is a significant complement of the quinine-thiourea catalyzed sulfa-Michael-Michael cascade reaction. The densely functionalized target thiochromans were obtained in high diastereoselectivities, and with high to excellent enantioselectivities.
