1353160-88-9 Usage
General Description
2-Azetidinepropanoic acid, 2-(Methoxycarbonyl)-1-(phenylMethyl)-, Methyl ester is a chemical compound with a complex name. It is an ester derivative of 2-Azetidinepropanoic acid, which belongs to the class of organic compounds known as fatty acid esters. This particular compound is composed of a 2-(methoxycarbonyl)-1-(phenylmethyl) group attached to a 2-azetidinepropanoic acid backbone, with a methyl ester attached to the carboxy group. 2-Azetidinepropanoic acid, 2-(Methoxycarbonyl)-1-(phenylMethyl)-, Methyl ester has potential biological activity and is commonly used in chemical research and as a building block for the synthesis of more complex molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1353160-88-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,3,1,6 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1353160-88:
(9*1)+(8*3)+(7*5)+(6*3)+(5*1)+(4*6)+(3*0)+(2*8)+(1*8)=139
139 % 10 = 9
So 1353160-88-9 is a valid CAS Registry Number.
1353160-88-9Relevant articles and documents
Synthesis of spirocyclopropyl γ-lactams by tandem intramolecular azetidine ring-opening/closing cascade reaction: Synthetic and mechanistic aspects
Nocquet, Pierre-Antoine,Hazelard, Damien,Compain, Philippe
, p. 4117 - 4128 (2012/07/28)
The scope and limitations of a novel intramolecular azetidine ring-opening/closing cascade reaction affording spirocyclopropyl γ-lactams from azetidines in high regio- and stereoselectivity is reported. The key step of the process is a SN2-type ring-opening of TMSOTf-activated azetidine rings by silyl ketene acetals generated by treatment with TMSOTf and TEA. This study is a very rare example of nucleophilic ring-opening of azetidines that does not require formation of quaternary azetidinium salts by N-alkylation or the use of N-electron-withdrawing groups. Application of this process to 2-azetidinone system led to a complete change in reactivity and provide 6-aza-bicyclo[3.2.0]heptane derivatives via an unprecedented Mukaiyama aldol-like reaction involving an ester acceptor and a silyl imidate.
