1353221-23-4Relevant academic research and scientific papers
Nickel(0) catalyzed oxidation of organosilanes to disiloxanes by air as an oxidant
Lv, Haiping,Laishram, Ronibala Devi,Li, Jiayan,Shi, Guangrui,Sun, Weiqing,Xu, Jianbin,Yang, Yong,Luo, Yang,Fan, Baomin
, p. 971 - 974 (2019)
We report here an efficient non-aqueous route to symmetrical disiloxanes from their corresponding organosilanes using Ni(COD)2 with 3,4,7,8-tetramethyl-1,10-phenanthroline in air. Our methodology is very simple and high yielding. The reaction mechanism is also proposed.
Aryl-aryl bond formation by the fluoride-free cross-coupling of aryldisiloxanes with aryl bromides
Boehner, Christine M.,Frye, Elizabeth C.,O'Connell, Kieron M. G.,Galloway, Warren R. J. D.,Sore, Hannah F.,Dominguez, Patricia Garcia,Norton, David,Hulcoop, David G.,Owen, Martin,Turner, Gillian,Crawford, Claire,Horsley, Helen,Spring, David R.
supporting information; experimental part, p. 13230 - 13239 (2012/02/06)
The prevalence of the biaryl structural motif in biologically interesting and synthetically important molecules has inspired considerable interest in the development of methods for aryl-aryl bond formation. Herein we describe a novel strategy for this process involving the fluoride-free, palladium-catalysed cross-coupling of readily accessible aryldisiloxanes and aryl bromides. Using a statistical-based optimisation process, preparatively useful reaction conditions were formulated to allow the cross-coupling of a wide range of different substrates. This methodology represents an attractive, cost-efficient, flexible and robust alternative to the traditional transition-metal-catalysed routes typically used to generate molecules containing the privileged biaryl scaffold.
