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135326-11-3

Gadoxetic acid, also known as Gd-EOB-DTPA, is a liver-specific magnetic resonance imaging (MRI) contrast agent that enhances the visualization and evaluation of liver lesions. It contains the paramagnetic gadolinium ion, which boosts the T1-weighted MRI signals in the liver, facilitating better identification and characterization of liver tumors and lesions. Gadoxetic acid is selectively taken up by hepatocytes and excreted into the bile, making it an effective tool for differentiating between malignant and benign liver lesions and for assessing liver function. It is generally well-tolerated, with common side effects being mild and transient, such as headache or nausea.

135326-11-3

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  • Gadolinate(2-),[N-[(2S)-2-[bis[(carboxy-kO)methyl]amino-kN]-3-(4-ethoxyphenyl)propyl]-N-[2-[bis[(carboxy-kO)methyl]amino-kN]ethyl]glycinato(5-)-kN,kO]-, hydrogen (1:2), (SA-8-11252634)-

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  • Gadolinate(2-),[N-[(2S)-2-[bis[(carboxy-kO)methyl]amino-kN]-3-(4-ethoxyphenyl)propyl]-N-[2-[bis[(carboxy-kO)methyl]amino-kN]ethyl]glycinato(5-)-kN,kO]-, hydrogen (1:2), (SA-8-11252634)-

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135326-11-3 Usage

Uses

Used in Medical Imaging Industry:
Gadoxetic acid is used as a liver-specific MRI contrast agent for enhancing the visualization and characterization of liver tumors and lesions. Its uptake by hepatocytes and excretion into the bile allows for better differentiation between malignant and benign liver lesions, as well as the evaluation of liver function.
Used in Diagnostic Applications:
Gadoxetic acid is employed as a diagnostic tool for identifying and differentiating liver lesions, including tumors and other abnormalities. Its ability to enhance T1-weighted MRI signals in the liver aids in the accurate diagnosis and monitoring of liver conditions.
Used in Liver Function Assessment:
Gadoxetic acid is utilized for evaluating liver function by assessing the uptake and excretion of the contrast agent by hepatocytes. This helps in determining the overall health and functionality of the liver, as well as identifying any potential issues or abnormalities.

Check Digit Verification of cas no

The CAS Registry Mumber 135326-11-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,3,2 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 135326-11:
(8*1)+(7*3)+(6*5)+(5*3)+(4*2)+(3*6)+(2*1)+(1*1)=103
103 % 10 = 3
So 135326-11-3 is a valid CAS Registry Number.
InChI:InChI=1/C23H33N3O11.Gd/c1-2-37-18-5-3-16(4-6-18)9-17(26(14-22(33)34)15-23(35)36)10-24(11-19(27)28)7-8-25(12-20(29)30)13-21(31)32;/h3-6,17H,2,7-15H2,1H3,(H,27,28)(H,29,30)(H,31,32)(H,33,34)(H,35,36);/q;+3/p-3/t17-;/m0./s1

135326-11-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Gadoxetic acid

1.2 Other means of identification

Product number -
Other names Gadoxetic

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:135326-11-3 SDS

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135326-11-3Related news

Liver enhancement in healthy dogs after Gadoxetic acid (cas 135326-11-3) administration during dynamic contrast-enhanced magnetic resonance imaging08/19/2019

Dynamic contrast enhanced (DCE)-magnetic resonance imaging (MRI) consists of acquisition of native baseline images, followed by a series of acquisitions performed during and after administration of a contrast medium. DCE-MRI, in conjunction with hepatobiliary-specific contrast media, such as gad...detailed

Relationship between transient severe motion of the liver in Gadoxetic acid (cas 135326-11-3) or iodinated contrast agent-enhanced imaging and arterial oxygen saturation and heart rate changes08/11/2019

PurposeTo clarify the relationship between transient sever motion artifact in arterial phase (TSMA) and changes in peripheral capillary oxygen saturation (SpO2) and heart rate (HR) after contrast media administration during MRI or CT of the liver.detailed

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