1353387-22-0Relevant articles and documents
Protein transduction domain mimics: The role of aromatic functionality
Som, Abhigyan,Reuter, Anika,Tew, Gregory N.
, p. 980 - 983 (2012)
For better or worse: Protein transduction domain mimics built from synthetic polymers demonstrate that aromatic side chains provide better transduction than aliphatic groups at the same relative hydrophobicity. Similarly, a less hydrophobic aromatic side chain is more active than the corresponding aliphatic one containing the same number of carbon atoms (see picture). Copyright
Protein transduction domains mimics
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Page/Page column 41-42, (2016/08/07)
The invention generally relates to synthetic mimics of cell penetrating peptides. More particularly, the invention relates to certain novel monomers, oligomers and polymers (e.g., co-polymers) that are useful for the preparation of synthetic mimics of cell penetrating peptides, their compositions, preparations and use.