135353-26-3Relevant articles and documents
Composition for treating depression with (N-heteroaryl)alkylamines
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, (2008/06/13)
The invention concerns compounds having formula: STR1 or a salt thereof, wherein E represents hydrogen, lower alkyl or a group Ar 1 --A 1 --; Ar and Ar 1 are the same or different aryl groups (including heteroaryl) which are optionally substituted, eg by one or more substituents commonly used in pharmaceutical chemistry; A and A 1 are the same or different alkylene groups having one or two carbon atoms linking Ar or Ar 1 to N and optionally substituted by lower alkyl and/or optionally substituted aryl, B is an alkylene group of 3 or 4 carbon atoms, which may be substituted by lower alkyl; D 1 represents halogen, CH 3, CR 1 R 2 NH 2, SO 3 H or SO 2 NR 6 R 7 where R 1 and R 2 are independently hydrogen or lower alkyl and R 6 and R 7 are each hydrogen, lower alkyl or aralkyl of 7 to 12 carbon atoms or R 6 and R 7 together with the nitrogen atom to which they are attached represent a 5 or 6 membered ring, which compounds are useful, for treating depression or cerebral insufficiency or dementias in animals.
