1353545-62-6

Upstream product

• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 56453-86-2 (E)-3-cyclohexylprop-2-enoic acid 

Downstream Products

• 1414349-09-9 (S)-4-benzyl-3-((S)-3-cyclohexyl-4,4,4-trifluorobutanoyl)oxazolidin-2-one 
• 1414349-08-8 (S)-4-benzyl-3-((R)-3-cyclohexyl-4,4,4-trifluorobutanoyl)oxazolidin-2-one 

Relevant academic research and scientific papers

Conjugate hydrotrifluoromethylation of α,β-unsaturated acyl-oxazolidinones: Synthesis of chiral fluorinated amino acids

A novel conjugate hydrofluoroalkylation of α,β-unsaturated acyl-oxazolidinones is described. Using this method, enantiomerically pure β-trifluoromethylated amino acids were prepared. Trifluorovaline and trifluoroisoleucine were incorporated into peptides and found to show extremely low α-helix propensities.