1353561-06-4Relevant articles and documents
Synthesis of 2-trifluoromethylpyrazolo[5,1-a]isoquinolines via silver triflate-catalyzed or electrophile-mediated one-pot tandem reaction
Zhou, Xiaoli,Liu, Meiling,Luo, Puying,Lai, Yingjun,Yan, Tangtao,Ding, Qiuping
, p. 2286 - 2292 (2014)
An efficient one-pot tandem cyclization/[3 + 2] cycloaddition reaction of N '-(2-alkynylbenzylidene)hydrazides with ethyl 4,4,4- trifluorobut-2-ynoate under silver triflate-catalyzed or electrophile-mediated conditions is described. Various trifluoromethy
An efficient approach to H-pyrazolo[5,1-a]isoquinolines via a silver triflate-catalyzed reaction of N′-(2-alkynylbenzylidene)hydrazide with allenoate
Gao, Liang,Ye, Shengqing,Ding, Qiuping,Chen, Zhiyuan,Wu, Jie
supporting information; experimental part, p. 2765 - 2769 (2012/04/23)
A silver triflate-catalyzed reaction of N′-(2-alkynylbenzylidene) hydrazide with allenoate under mild conditions is described, which provides an efficient approach to diverse H-pyrazolo[5,1-a]isoquinolines. This reaction proceeds with a wide substrate sco
Synthesis of isoquinolinium-2-yl amides via silver(I)-catalyzed ring closure of N′-(2-alkynylbenzylidene)hydrazides
Peshkov, Vsevolod A.,Pereshivko, Olga P.,Vanhove, Sofie,Ermolatev, Denis S.,Vandereycken, Erik V.
supporting information; experimental part, p. 3371 - 3374 (2011/11/30)
An efficient one-pot protocol for the synthesis of isoquinolinium-2-yl amides starting from readily available hydrazides and 2-alkynylbenzaldehydes is described. The key step of the protocol is a silver(I)-catalyzed ring-closure of N-(2-alkynylbenzylidene)hydrazides that are generated in situ. Isoquinolinium-2-yl amides derived from tert-butoxycarbonyl hydrazide could be further deprotected, delivering 2-aminoisoquinolinium trifluoroacetates. Georg Thieme Verlag Stuttgart · New York.
