1353565-41-9Relevant academic research and scientific papers
A transition metal-free tandem process to pyrrolopyrazino[2,3-d]pyridazine- diones
Huang, Aiping,Qiao, Zhi,Zhang, Xinhai,Yu, Wei,Zheng, Qingqing,Ma, Ying,Ma, Chen
experimental part, p. 906 - 912 (2012/01/14)
A transition metal-free tandem process for the synthesis of pyrrolopyrazino[2,3-d]pyridazine-diones is described. The process is an efficient construction of this tricyclic system by a one-pot coupling/Smiles rearrangement/cyclization approach. This methodology has potential applications in the synthesis of biologically and medicinally relevant compounds.
