1353567-82-4Relevant academic research and scientific papers
Synthesis of unique analogues of the ergoline skeleton using intramolecular [3+2] cycloaddition
Picard, Sébastien,Lecornué, Frédéric,Bashiardes, Georges
, p. 1106 - 1110 (2014)
A new methodology is described for the novel and rapid synthesis of unique analogues of the ergoline structure. After introduction of an allyl or alkynyl group in position C-4 on indole-3-carboxaldehyde, an intramolecular 1,3-dipolar cycloaddition using α-amino esters, directly provides novel ergoline-type compounds in good yields. Georg Thieme Verlag Stuttgart New York.
