1353682-93-5 Usage
General Description
(1R)-3,3'-bis[3,5-bis(1,1-dimethylethyl)-4-methoxyphenyl]-[1,1'-Binaphthalene]-2,2'-diol, also known as Bisbenzavitriol, is a chemical compound that belongs to the binaphthol family. It is a chiral molecule with two chiral centers, and it exists as a white to off-white powder. Bisbenzavitriol is commonly used as a chiral auxiliary in asymmetric synthesis, particularly in the construction of complex organic molecules such as natural products and pharmaceuticals. It has been found to be effective in promoting a variety of asymmetric reactions, including Diels-Alder reactions, aldol reactions, and cycloadditions. Bisbenzavitriol has also shown potential in catalyzing the highly enantioselective addition of diethylzinc to aldehydes and is widely used in academic and industrial settings for its utility in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1353682-93-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,3,6,8 and 2 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1353682-93:
(9*1)+(8*3)+(7*5)+(6*3)+(5*6)+(4*8)+(3*2)+(2*9)+(1*3)=175
175 % 10 = 5
So 1353682-93-5 is a valid CAS Registry Number.
1353682-93-5Relevant articles and documents
A Ruthenium/Phosphoramidite-Catalyzed Asymmetric Interrupted Metallo-ene Reaction
Trost, Barry M.,Ryan, Michael C.
supporting information, p. 2981 - 2984 (2016/03/19)
Allylic chlorides prepared from commercially available trans-1,4-dichloro-2-butene were converted to trans-disubstituted 5- and 6-membered ring systems with perfect diastereoselectivity and high enantioselectivity under chiral ruthenium catalysis. These products contain stereodefined secondary and tertiary alcohols that originate from the trapping of an alkylruthenium intermediate with adventitious water. Key to the success of this transformation was the development of a new BINOL-based phosphoramidite ligand containing bulky substitution at its 3- and 3′-positions. As a demonstration of product utility, diastereoselective Friedel-Crafts reactions were performed on the chiral benzylic alcohols in high yield and stereoselectivity.
