135369-32-3

Basic information

• Product Name: tetrahydro-3-oxo-2H-thiopeyran-4-carboxylic acid ethyl ester
• Synonyms: tetrahydro-3-oxo-2H-thiopeyran-4-carboxylic acid ethyl ester
• CAS NO: 135369-32-3
• Molecular Formula: C₈H₁₂O₃S
• Molecular Weight: 188.24408
• Mol File: 135369-32-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 281.8±40.0 °C(Predicted)
• Appearance: /
• Density: 1.202±0.06 g/cm3(Predicted)
• PKA: 10.26±0.20(Predicted)
• CAS DataBase Reference: tetrahydro-3-oxo-2H-thiopeyran-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: tetrahydro-3-oxo-2H-thiopeyran-4-carboxylic acid ethyl ester(135369-32-3)
• EPA Substance Registry System: tetrahydro-3-oxo-2H-thiopeyran-4-carboxylic acid ethyl ester(135369-32-3)

Safety Data

• Hazardous Substances Data: 135369-32-3(Hazardous Substances Data)

Upstream product

• 63449-37-6 ethyl 4-<(2-ethoxy-2-oxoethyl)sulfanyl>butanoate 

Downstream Products

• 135369-43-6 10-Benzyl-6,7-dihydro-2-methylthio-9H,10H-thiopyrano<3,4-d>-1,2,4-triazolo<1,5-a>pyrimidin-5-one 
• 135369-44-7 10-Benzyl-7,8-dihydro-2-methylthio-5H,10H-thiopyrano<4,3-e>-1,2,4-triazolo<1,5-a>pyrimidin-9-one 

Relevant articles and documents

Lead optimisation of selective non-zinc binding inhibitors of MMP13. Part 2

Directed screening has identified a novel series of non-zinc binding MMP13 inhibitors that possess good levels of activity whilst demonstrating excellent selectivity over related MMPs. A lead optimisation campaign has delivered compounds with enhanced MMP